Tumor necrosis factor α and lymphotoxin α haplotypes in idiopathic recurrent pregnancy loss
| dc.contributor.author | Zammiti, Walid | |
| dc.contributor.author | Mtiraoui, Nabil | |
| dc.contributor.author | R Finan, Ramzi | |
| dc.contributor.author | Y Almawi, Wassim | |
| dc.contributor.author | Mahjoub, Touhami | |
| dc.date.accessioned | 2022-03-08T07:53:30Z | |
| dc.date.accessioned | 2023-08-19T08:53:46Z | |
| dc.date.available | 2022-03-08T07:53:30Z | |
| dc.date.available | 2023-08-19T08:53:46Z | |
| dc.date.issued | 2009-05 | |
| dc.description.abstract | Objective To investigate the contribution of the −238G/A and −308G/A tumor necrosis factor (TNF) α, and +252A/G lymphotoxin (LT) α gene polymorphisms to idiopathic recurrent miscarriage (RM). Design A retrospective case-control study. Setting Outpatient maternity center. Patient(s) Study subjects comprised 372 RM women and 274 age-matched parous control women. Intervention(s) None. Main Outcome Measure(s) The TNFα and LTα gene variants and idiopathic RM. Result(s) Higher prevalence of TNFα −238A and LTα +252G alleles and LTα +252G/G genotype and lower frequencies of TNFα −308G/A were seen in RM cases. Three-loci haplotype analysis (TNFα −308GA/TNFα −238GA/LTα +252AG) demonstrated significant association between TNFα-LTα gene variants and RM | en_US |
| dc.identifier.citation | Zammiti, W., Mtiraoui, N., Finan, R. R., Almawi, W. Y., & Mahjoub, T. (2009). Tumor necrosis factor α and lymphotoxin α haplotypes in idiopathic recurrent pregnancy loss. Fertility and sterility, 91(5), 1903-1908. | en_US |
| dc.identifier.doi | https://doi.org/10.1016/j.fertnstert.2008.01.090 | |
| dc.identifier.uri | https://edms.wexl.in/handle/1/2859 | |
| dc.language.iso | en | en_US |
| dc.publisher | Elsevier | en_US |
| dc.subject | Tumor necrosis factor | en_US |
| dc.subject | Lymphotoxinre current miscarriage | en_US |
| dc.subject | Gene | en_US |
| dc.title | Tumor necrosis factor α and lymphotoxin α haplotypes in idiopathic recurrent pregnancy loss | en_US |
| dc.title.alternative | Fertility and sterility | en_US |
| dc.type | Article | en_US |
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