Micronutrient Status in Pregnant Women after Metabolic Bariatric Surgery in the United Arab Emirates: A Prospective Study
| dc.contributor.author | Al Mansoori,Amna | |
| dc.contributor.author | I Ali, Habiba | |
| dc.contributor.author | Al Momani, Hazem | |
| dc.contributor.author | F Bataineh, Mo’ath | |
| dc.date.accessioned | 2025-11-10T09:28:52Z | |
| dc.date.available | 2025-11-10T09:28:52Z | |
| dc.date.issued | 2023 | |
| dc.description | Pre-pregnancy obesity is a risk factor for various maternal and fetal outcomes, such as labor induction, miscarriage, and gestational diabetes [1,2]. Different interventions, such as diet, exercise, and medications, fail to manage the weight of individuals with obesity (body mass index [BMI] ≥ 40 kg/m2) [3,4]. Hence, metabolic bariatric surgery (MBS) is increasingly used to treat morbidities in individuals with obesity. There is a well-established association between the perinatal environment and potential future disease [5,6,7,8,9,10,11]. Adequate maternal nutrition is crucial for fetal growth and development [12,13]. It supports the physiological demands of the body to support the placenta and offspring during pregnancy [12]. Pregnant women with a history of MBS have been found to experience micronutrient deficiencies [14,15,16,17,18,19], with the most common being vitamin B12 and D deficiencies [20]. | |
| dc.description.abstract | Abstract Metabolic bariatric surgery (MBS) helps reduce comorbidities, such as hypertension and gestational diabetes, and is more effective than diet management for women with obesity-related health issues. Vitamin B12, vitamin D, and iron play important roles in ensuring the health of a neonate. However, pregnancies occurring after MBS may face complications related to micronutrient deficiencies, particularly of vitamins B12 and D and iron. This study aimed to investigate the vitamin B12, vitamin D, ferritin, and iron status of pregnant women who underwent MBS compared with women without MBS history. The study included 217 pregnant women (105 with a history of MBS and 112 without a history of MBS) who visited a major maternity hospital in Abu Dhabi, United Arab Emirates (UAE) between July 2021 and November 2022. The maternal vitamin B12, vitamin D, iron, and ferritin levels were measured twice, initially during the first or second trimester and subsequently during the third trimester. The iron was measured once during the pregnancy. Vitamin B12 deficiency was higher among pregnant women with MBS history compared to non-bariatric pregnant women (24.4% vs. 3.9%, p < 0.001). Women with a history of MBS had a higher prevalence of vitamin D deficiency (62.3% vs. 37.7%, p < 0.002). Linear regression analysis indicated that vitamin B12 levels decreased by 55 pg/mL in women with a history of MBS and by 4.6 pg/mL with a unit increase in body mass index (kg/m2). Furthermore, vitamin D levels in women with a history of MBS decreased by 4.9 ng/mL during pregnancy. Metabolic bariatric surgery is associated with vitamin B12, vitamin D, and iron deficiencies during pregnancy. Keywords: bariatric surgery, pregnancy, vitamin B12, vitamin D, iron | |
| dc.identifier.citation | Al Mansoori, A., Bataineh, M. A. F., Al Momani, H., & Ali, H. I. (2023). Micronutrient Status in Pregnant Women after Metabolic Bariatric Surgery in the United Arab Emirates: A Prospective Study. Nutrients, 16(1), 72. | |
| dc.identifier.doi | ; https://doi.org/10.3390/nu16010072 | |
| dc.identifier.uri | https://repository.adu.ac.ae/handle/1/7678 | |
| dc.language.iso | en | |
| dc.publisher | MDPI | |
| dc.title | Micronutrient Status in Pregnant Women after Metabolic Bariatric Surgery in the United Arab Emirates: A Prospective Study | |
| dc.type | Article |