Integrated Phytochemical Profiling, UPLC-HRMS Characterization, and Bioactivity Evaluation of Zingiber officinale and Piper nigrum
| dc.contributor.author | Boubker, Aicha | |
| dc.contributor.author | El Ouardi, Abdelmoula | |
| dc.contributor.author | El Kamli, Taha | |
| dc.contributor.author | Kaicer, Mohammed | |
| dc.contributor.author | Kichou, Faouzi | |
| dc.contributor.author | Errafii, Khaoula | |
| dc.contributor.author | ETAL.. | |
| dc.date.accessioned | 2025-10-14T12:30:54Z | |
| dc.date.available | 2025-10-14T12:30:54Z | |
| dc.date.issued | 2025-08-12 | |
| dc.description | For centuries, medicinal plants have served as essential components of traditional healthcare systems, valued for their therapeutic and preventive benefits. In the context of the COVID-19 pandemic, renewed interest has emerged regarding their potential to support recovery, particularly due to their anti-inflammatory and antioxidant activities. These properties may help alleviate post-infection symptoms and support physiological homeostasis during the recovery period [1]. During the pandemic, spice consumption increased significantly in surveyed populations, including notable rises in the use of condiments and spices such as ginger and black pepper during lockdowns [2,3]. The increasing global interest in spice-derived compounds has recently stimulated advances in plant genomics, aimed at improving both the sustainability and efficiency of their cultivation. | |
| dc.description.abstract | The phytochemical profiles, antioxidant capacities, mineral composition, and antibacterial activities of Zingiber officinale (Z. officinal) and Piper nigrum (P. nigrum) were explored through aqueous, ethanolic, and methanolic extractions. The extracts were analyzed for polyphenols, flavonoids, and tannins, and their antioxidant potential was assessed using the DPPH assay. UPLC-HRMS identified major bioactive compounds, including 6-gingerol and shogaol in Z. officinale, and piperine and piperlonguminine in P. nigrum. Mineral analysis showed that P. nigrum was particularly rich in essential elements, including calcium (Ca), magnesium (Mg), and iron (Fe). In antibacterial testing, P. nigrum demonstrated wider zones of inhibition against E. coli, whereas Z. officinale was more active at lower concentrations, showing MICs as low as 3.91 µg/mL against Salmonella and S. aureus. PCA analysis revealed strong correlations between phenolic content and biological effects. These results underscore the potential of both spices as effective natural agents for use in food preservation and health-promoting applications. Keywords: Phytochemical, Antimicrobial Activities, Antioxidant Activity, Z. Officinale, P. Nigrum, Polyphenols, Flavonoids, Tannin, Trace Elements, UPLC-HRMS Orbitrap | |
| dc.identifier.citation | Boubker, A., El Ouardi, A., El Kamli, T., Kaicer, M., Kichou, F., Errafii, K., ... & Sifou, A. (2025). Integrated Phytochemical Profiling, UPLC-HRMS Characterization, and Bioactivity Evaluation of Zingiber officinale and Piper nigrum. International Journal of Molecular Sciences, 26(16), 7782. | |
| dc.identifier.doi | https://doi.org/10.3390/ijms26167782 | |
| dc.identifier.uri | https://repository.adu.ac.ae/handle/1/7601 | |
| dc.language.iso | en | |
| dc.publisher | MDPI | |
| dc.title | Integrated Phytochemical Profiling, UPLC-HRMS Characterization, and Bioactivity Evaluation of Zingiber officinale and Piper nigrum | |
| dc.type | Article |