Influence of common and specific HLA-DRB1/DQB1 haplotypes on genetic susceptibilities of three distinct Arab populations to type 1 diabetes

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dc.contributor.authorStayoussef, Mouna
dc.contributor.authorBenmansour, Jihen
dc.contributor.authorA Al-Jenaidi, Fayza
dc.contributor.authorNemr, Rita
dc.contributor.authorE Ali, Muhallab
dc.contributor.authorMahjoub, Touhami
dc.contributor.authorY Almawi, Wassim
dc.date.accessioned2022-03-07T08:16:25Z
dc.date.accessioned2023-08-19T08:56:44Z
dc.date.available2022-03-07T08:16:25Z
dc.date.available2023-08-19T08:56:44Z
dc.date.issued2009-10
dc.description.abstractThe contribution of HLA DRB-DQB to type 1 diabetes (T1D) in Bahrainis, Lebanese, and Tunisians was investigated. DRB1*030101-DQB1*0201 was a locus that conferred susceptibility in three populations, while DRB1*040101-DQB1*0302 was a locus that conferred susceptibility only in Tunisians and Bahrainis. The DRB1*100101-DQB1*050101 (Bahrainis) and DRB1*150101-DQB1*060101 (Lebanese) loci were largely protective. The contribution of HLA to T1D must be evaluated with regard to ethnic background.en_US
dc.identifier.citationStayoussef, M., Benmansour, J., Al-Jenaidi, F. A., Nemr, R., Ali, M. E., Mahjoub, T., & Almawi, W. Y. (2009). Influence of common and specific HLA-DRB1/DQB1 haplotypes on genetic susceptibilities of three distinct Arab populations to type 1 diabetes. Clinical and Vaccine Immunology, 16(1), 136-138.en_US
dc.identifier.doihttps://doi.org/10.1128/CVI.00215-08
dc.identifier.urihttps://edms.wexl.in/handle/1/2846
dc.language.isoenen_US
dc.publisherAmerican Society for Microbiologyen_US
dc.subjectType 1 diabetesen_US
dc.subjectHLA DRB-DQBen_US
dc.subjectGeneticen_US
dc.subjectArab populationsen_US
dc.titleInfluence of common and specific HLA-DRB1/DQB1 haplotypes on genetic susceptibilities of three distinct Arab populations to type 1 diabetesen_US
dc.title.alternativeClinical and Vaccine Immunologyen_US
dc.typeArticleen_US

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