Transcription factor-7-like 2 gene variants are strongly associated with type 2 diabetes in Lebanese subjects

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dc.contributor.authorNemr, Rita
dc.contributor.authorTurki, Amira
dc.contributor.authorEchtay, Akram
dc.contributor.authorS Al-Zaben, Ghadeer
dc.contributor.authorS Daher, Hoda
dc.contributor.authorA Irani-Hakime, Noha
dc.contributor.authorH Keleshian, Sose
dc.contributor.authorY Almawi, Wassim
dc.date.accessioned2022-03-09T10:54:55Z
dc.date.accessioned2023-08-19T08:57:06Z
dc.date.available2022-03-09T10:54:55Z
dc.date.available2023-08-19T08:57:06Z
dc.date.issued2012
dc.description.abstractWe tested the association of TCF7L2 variants with type 2 diabetes (T2DM) in 691 Lebanese people and 919 controls. rs7901695, rs4506565, rs7903146, rs12243326, rs7895340, and rs12255372 minor allele frequencies were higher in T2DM. Haplotype analysis (rs7901695–rs4506565–rs7903146–rs12243326–rs7895340–rs11196205–rs12255372) identified positively- (2122112, 2222222) and negatively- (1111111) T2DM-associated haplotypes. TCF7L2 is a common T2DM candidate gene in Lebanese people.en_US
dc.identifier.citationNemr, R., Turki, A., Echtay, A., Al-Zaben, G. S., Daher, H. S., Irani-Hakime, N. A., ... & Almawi, W. Y. (2012). Transcription factor-7-like 2 gene variants are strongly associated with type 2 diabetes in Lebanese subjects. Diabetes research and clinical practice, 98(3), e23-e27.en_US
dc.identifier.doihttps://doi.org/10.1016/j.diabres.2012.09.044
dc.identifier.urihttps://edms.wexl.in/handle/1/2879
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.subjectDiabetesen_US
dc.subjectGenome wide associationen_US
dc.subjectReplicationen_US
dc.subjectTCF7L2en_US
dc.titleTranscription factor-7-like 2 gene variants are strongly associated with type 2 diabetes in Lebanese subjectsen_US
dc.title.alternativeDiabetes research and clinical practiceen_US
dc.typeArticleen_US

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