Effect of sunflower oil nanoemulsions on the growth and lifespan extension of the Caenorhabditis elegans

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dc.contributor.authorIqbal R.
dc.contributor.authorAsghar W.
dc.contributor.authorMehmood Z.
dc.contributor.authorETAL..
dc.date.accessioned2024-08-16T06:33:07Z
dc.date.available2024-08-16T06:33:07Z
dc.date.issued2024
dc.descriptionCaenorhabditis elegans is a non-parasitic, small (1 mm in length), transparent, and free-living roundworm nematode with cosmopolitan distribution (Schulenburg and Félix 2017), a short life cycle of 3 days from egg stage to adulthood at 25oC, and a total lifespan of between 2-3 weeks, permitting ease of genetic manipulation, and facilitation in terms of the study of its biological attributes (Alexander et al.,
dc.description.abstractCaenorhabditis elegans has been used as a central model system for broad-spectrum research studies across diverse modern biological domains. A study was conducted to evaluate the potential of sunflower oil-based nanoemulsions for lifespan enhancement in stressed C. elegans worms, that had been fed on nematode growth media (NGM) seeded with two strains of pathogenic bacteria (Salmonella enterica serovar Typhimurium and Staphylococcus aureus). Nanoemulsions were fabricated using HI-CAP® 100 modified food starch, and their stability was tested under different processing conditions (temperature, pH, ionic strength) over a period of 5 months. Lifespan assay results demonstrated that sunflower-oil-based nanoemulsions with droplet size 170.2±9.3 nm, significantly facilitated the growth of C. elegans under stress conditions and increased the lifespan of the worms from the previously recorded 11 days to 26 days in the current research study. Keywords: Caenorhabditis Elegans, Food-Grade Nanoemulsions, Lifespan Extension, Stability
dc.identifier.doihttps://doi.org/10.26656/fr.2017.8(1).073
dc.identifier.urihttps://repository.adu.ac.ae/handle/1/6212
dc.language.isoen
dc.publisherRynnye Lyan Resources
dc.titleEffect of sunflower oil nanoemulsions on the growth and lifespan extension of the Caenorhabditis elegans
dc.typeArticle

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