Identification of a novel HLA-A allele, HLA-A*01:195, in a UAE national

Simple item page
dc.contributor.authorAbdrabou, Wael
dc.contributor.authorWitzel, Ini-Isabée
dc.contributor.authorPaduch, Agnieszka
dc.contributor.authorE.T.A.L..
dc.date.accessioned2025-10-07T09:16:03Z
dc.date.available2025-10-07T09:16:03Z
dc.date.issued2016-07
dc.descriptionThe human leukocyte antigen (HLA) genes are the most polymorphic genes in the human genome and play key roles in immunogenetics and histocompatibility.
dc.description.abstractA novel human leucocyte antigen (HLA)-A allele, HLA-A*01:195, was identified by sequence-based typing (SBT) in a UAE national subject. The novel allele is identical to its closest known allele, HLA-A*01:01:01:01, in exon 2, 3 and 4, except for a single nucleotide mutation of A to G at position 442 in exon 3 (codon 124 in the α2 domain of the α chain of the mature protein). This A to G mutation results in an amino acid change of isoleucine #124 to valine. Keywords: Human Leucocyte Antigen, UAE National, Immunogenetics, Chromosome
dc.identifier.citationAbdrabou, W., Witzel, I. I., Paduch, A., Tay, G., & Alsafar, H. (2016). Identification of a novel HLA-A allele, HLA-A* 01: 195, in a UAE national. Human Immunology, 77(7), 605-608.
dc.identifier.doihttps://doi.org/10.1016/j.humimm.2016.05.010
dc.identifier.urihttps://repository.adu.ac.ae/handle/1/7573
dc.language.isoen
dc.publisherElsevier
dc.titleIdentification of a novel HLA-A allele, HLA-A*01:195, in a UAE national
dc.typeArticle

Files

License bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed to upon submission
Description:
Download

Collections

Genetic