Therapeutic Potential of Marine Bioactive Peptides against Human Immunodeficiency Virus: Recent Evidence, Challenges, and Future Trends
| dc.contributor.author | Khalid, Nauman | |
| dc.contributor.author | Alessa, Fatima | |
| dc.contributor.author | Al-Mssallem, Muneera | |
| dc.contributor.author | ETAL.. | |
| dc.date.accessioned | 2024-10-21T07:31:31Z | |
| dc.date.available | 2024-10-21T07:31:31Z | |
| dc.date.issued | 2022-07 | |
| dc.description | Research in recent decades has highlighted the potential of natural bioactive compounds for the clinical management of various diseases, such as acquired immunodeficiency syndrome (AIDS), caused by the human immunodeficiency virus (HIV) [1]. Marine bioactive peptides (MBAPs) that are present in many marine species, including fish, sponges, cyanobacteria, fungi, ascidians, seaweeds, and mollusks, have gained attention for their health-promoting benefits. MBAPs obtained from marine species have ameliorating potential against many health conditions, such as hypertension, diabetes, obesity, HIV, cancer, oxidation, and inflammation. | |
| dc.description.abstract | Acquired immunodeficiency syndrome (AIDS) is a chronic and potentially fatal ailment caused by the human immunodeficiency virus (HIV) and remains a major health problem worldwide. In recent years, the research focus has shifted to a greater emphasis on complementing treatment regimens involving conventional antiretroviral (ARV) drug therapies with novel lead structures isolated from various marine organisms that have the potential to be utilized as therapeutics for the management of HIV-AIDS. The present review summarizes the recent developments regarding bioactive peptides sourced from various marine organisms. This includes a discussion encompassing the potential of these novel marine bioactive peptides with regard to antiretroviral activities against HIV, preparation, purification, and processing techniques, in addition to insight into the future trends with an emphasis on the potential of exploration and evaluation of novel peptides to be developed into effective antiretroviral drugs. Keywords:bioactive peptides; anti-HIV; marine organisms; antiretroviral agents; drugs | |
| dc.identifier.citation | Al-Khayri, J. M., Asghar, W., Khan, S., Akhtar, A., Ayub, H., Khalid, N., ... & Shehata, W. F. (2022). Therapeutic potential of marine bioactive peptides against human immunodeficiency virus: Recent evidence, challenges, and future trends. Marine Drugs, 20(8), 477. | |
| dc.identifier.doi | https://doi.org/10.3390/md20080477 | |
| dc.identifier.uri | https://repository.adu.ac.ae/handle/1/6803 | |
| dc.language.iso | en | |
| dc.publisher | MDPI | |
| dc.title | Therapeutic Potential of Marine Bioactive Peptides against Human Immunodeficiency Virus: Recent Evidence, Challenges, and Future Trends | |
| dc.type | Article |