Antibacterial activity of the venom of Heterometrus xanthopus
| dc.contributor.author | Ahmed, Umair | |
| dc.contributor.author | Rehman, Malik Mujaddad-ur | |
| dc.contributor.author | khal | |
| dc.contributor.author | Fawad, Sardar Atiq | |
| dc.contributor.author | Fatima, Anees | |
| dc.date.accessioned | 2023-04-05T08:33:55Z | |
| dc.date.accessioned | 2023-08-19T08:50:53Z | |
| dc.date.available | 2023-04-05T08:33:55Z | |
| dc.date.available | 2023-08-19T08:50:53Z | |
| dc.date.issued | 2012-08 | |
| dc.description | Scorpions are venomous arthropod animals belonging to the class Arachnida.[1] There are thirteen families and about 1,400 described species and subspecies of scorpions.[2] All scorpions are venomous but approximately 50 of them have enough poison to kill a person.[3,4] The oldest known scorpions lived around 430 million years ago in the Silurian period, on the bottom of shallow tropical seas, hence regarded as the oldest terrestrial arthropods | en_US |
| dc.description.abstract | Heterometrus xanthopus (Scorpion) is one of the most venomous and ancient arthropods. Its venom contains anti-microbial peptides like hadrurin, scorpine, Pandinin 1, and Pandinin 2 that are able to effectively kill multidrug-resistant pathogens. The present study was conducted to evaluate the anti-bacterial activity of H. xanthopus venom. Six Gram-positive and Gram-negative bacterial strains were tested against 1/100, 1/10, and 1/1 fractions of distilled water diluted and crude venom. 1/100 and 1/10 dilutions were not successful in any of the six bacterial strains studied while the 1/1 dilution was effective on Bacillus subtilis ATCC 6633, Salmonella typhimurium ATCC 14028, and Pseudomonas aeruginosa ATCC 27853 with highest zone of inhibition were obtained on B. subtilis. Crude venom was effective against Enterococcus faecalis ATCC 14506, B. subtilis, S. typhimurium, and P. aeruginosa. The most effective results were observed on B. subtilis. | en_US |
| dc.identifier.citation | Ahmed, U., Mujaddad-ur-Rehman, M., Khalid, N., Fawad, S. A., & Fatima, A. (2012). Antibacterial activity of the venom of Heterometrus xanthopus. Indian Journal of Pharmacology, 44(4), 509. | en_US |
| dc.identifier.doi | https://doi.org/10.4103%2F0253-7613.99332 | |
| dc.identifier.uri | https://edms.wexl.in/handle/1/4488 | |
| dc.language.iso | en | en_US |
| dc.publisher | Pub Med Central | en_US |
| dc.subject | Antibiotics | en_US |
| dc.subject | Antimicrobial activity | en_US |
| dc.subject | Extracts | en_US |
| dc.subject | Heterometrus xanthopus venom | en_US |
| dc.title | Antibacterial activity of the venom of Heterometrus xanthopus | en_US |
| dc.title.alternative | Indian Journal of Pharmacology | en_US |
| dc.type | Article | en_US |